FIG. 4.

Cartoon showing peptide binding to a homogeneous bilayer (left) and desorption from a bilayer with PG domains induced by 6W-RP-1 binding (right). Red headgroups represent unmodified PG; blue headgroups represent lysyl-PG; white headgroups represent PC. In the left panel, peptides are drawn as gray, random structures above the bilayer, representing the unfolded state in solution; in the right panel, they are shown as gray rods to indicate their more ordered conformation in association with the bilayer-bound state.