TABLE 3.
Underlying condition (no. of patients) | Median (range) duration of voriconazole therapy (days) | No. (%) with clinical response | Median (range) survival (days) | No. that died (no. that died due to IFI) |
---|---|---|---|---|
HSCT (13) | 18 (3-182) | 5 (38) | 27 (6-202) | 9 (4) |
HMa (44) | 61 (1-480) | 20 (45) | 112 (4-808) | 27 (15) |
Chronicb (9) | 57 (3-267) | 4 (44) | 200 (6-435) | 5 (3) |
Otherc (7) | 30 (19-259) | 5 (71) | Not reached (19-365) | 2 (0) |
Total (73) | 57 (1-480) | 34 (47) | 120 (4-808) | 43 (22) |
HM, hematologic malignancy.
Chronic conditions included lymphoma (3 patients), aplastic anemia (3), tumor lysis syndrome (1), neuroblastoma (1), and kidney transplant (1).
Other conditions were immunocompetence (4 patients), diabetes mellitus (2), paralytic ileus (1), and burns (1).