TABLE 4.
Comparisons of outcomes for invasive fusariosis cases treated with voriconazole
| Comparison (statistical method)a | No. with clinical response/total no. of patients (%) | P value |
|---|---|---|
| Male vs female (C) | 21/48 (44) vs 13/25 (52) | NSb |
| Proven vs probable infection (C) | 31/67 (46) vs 4/6 (67) | NS |
| Primary vs salvage/unknown therapy (C) | 7/16 (44) vs 27/57 (47) | NS |
| Combination vs voriconazole alone/unknown (C) | 6/13 (46) vs 28/60 (47) | NS |
| Voriconazole database vs NRCMA (C) | 20/39 (51) vs 14/34 (41) | NS |
| Neutropenia (F) | ≤0.03c | |
| Recent | 17/47 (36) | |
| None | 5/7 (71) | |
| Status unknown | 12/19 (63) | |
| Fusarium species (F) | NS | |
| F. solani complex | 9/16 (56) | |
| F. moniliforme complex | 2/8 (25) | |
| F. proliferatum complex | 4/8 (50) | |
| F. oxysporum complex | 6/7 (86) | |
| All other Fusarium spp. | 13/34 (38) |
a
C, chi-square test; F, Fisher's exact test.
b
NS, not significant.
c
P value for outcome in patients with neutropenia versus patients without neutropenia or with neutropenia status unknown.