TABLE 5.
Bacteriological success rates for the most common typical and atypical pathogens isolated at baseline and their in vitro susceptibilities (Eval-bITT population)
| Baseline pathogen (n)a | Bacteriological success/organisms isolated at baseline (%) |
MIC range baseline (μg/ml) |
|||
|---|---|---|---|---|---|
| Nemonoxacin |
Levofloxacin 500 mg | Nemonoxacin | Levofloxacin | ||
| 750 mg | 500 mg | ||||
| Typical pathogens | |||||
| H. influenzae (17) | 5/6 (83.3) | 4/4 (100.0) | 7/7 (100.0) | ≤0.008-0.06 | ≤0.008-0.03 |
| S. pneumoniae (14) | 5/5 (100.0) | 3/4 (75.0) | 5/5 (100.0) | 0.06-0.12 | 0.5-1.0 |
| S. aureus (4) | 1/1 (100.0) | 2/2 (100.0) | 1/1 (100.0) | 0.03-0.06 | 0.12-0.5 |
| Atypical pathogens | |||||
| M. pneumoniae (93) | 26/29 (89.7) | 25/31 (80.6) | 31/33 (93.9) | ||
| C. pneumoniae (23) | 8/8 (100.0) | 8/8 (100.0) | 6/7 (85.7) | ||
| L. pneumophila (8) | 3/3 (100.0) | 2/2 (100.0) | 3/3 (100.0) | ||
a
n, number of isolates.