Skip to main content
. 2010 Jul 19;54(10):4269–4274. doi: 10.1128/AAC.00420-10

FIG. 1.

FIG. 1.

A trisubstituted pyrrole (inset) inhibits the development of P. berghei sporozoites into LS in HepG2 cells. (A) Dose-dependent effect of the trisubstituted pyrrole on P. berghei sporozoite development into LS (40 h p.i.) in HepG2 cells, when present for the first 12 h of infection. (B) Dose-dependent effect of the trisubstituted pyrrole on P. berghei sporozoite development into LS (40 h p.i.) in HepG2 cells, when present for the first 3 h of infection. (C) Effect on sporozoites of addition of 10 μM trisubstituted pyrrole to HepG2 cells 3 h p.i. Each experiment was done at least thrice, each time in duplicate. Results of a representative experiment are shown. Error bars represent standard deviations (P > 0.05 relative to untreated group, t test).