FIG. 2.
A trisubstituted pyrrole inhibits invasion of host cells by P. berghei sporozoites. (A) Dose-dependent inhibition of P. berghei sporozoite invasion of HepG2 cells by the trisubstituted pyrrole. (B) Effect of the trisubstituted pyrrole on the motility of P. berghei sporozoites (P > 0.05 relative to untreated group, t test). (C) Effect of the trisubstituted pyrrole on the quality of trails deposited by P. berghei sporozoites. Each experiment was done at least thrice, each time in duplicate. Results from a representative experiment are shown. Error bars represent standard deviations.