FIG. 1.

Kinetics of bactericidal activity of transferrins. P. aeruginosa cells (10⁶ cells/ml) were incubated (37°C) with 0.125 μM (○), 0.5 μM (□), or 1 μM (▾) lactoferrin (A) or with 1 μM (○), 2 μM (□), or 4 μM (▾) transferrin (B). L. lactis cells (10⁶ cells/ml) were incubated (30°C) with 0.031 μM (○), 0.062 μM (□), or 0.125 μM (▾) lactoferrin (C) or with 4 μM (○) or 25 μM (□) transferrin (D). At the given time points, aliquots were plated, and colonies were counted after 24 h. The results are means ± SD for duplicates of at least three independent experiments.