FIG. 6.

A two-dose protocol, with doses being administered 1 day before and 1 day after JEV infection, gives the best protective effect. Glycolipid C34 (A) or 7DW8-5 (B) was administered to 7-week-old C57BL/6 mice by a two-dose protocol, as described in the legend to Fig. 4 [day (−1) & day (+1)] or only once 1 day before [day (−1)], on the same day [day (0)], or 1 day after [day (+1)] viral infection. The mice were challenged and monitored as described in the legend to Fig. 4. The percent survival and the number of mice in each experimental group are shown in the key above each panel.