TABLE 2.
PK results for daptomycin, vancomycin, moxifloxacin, clarithromycin, and rifampin obtained with the PK/PD model
Antimicrobial agent | fCmax (μg/ml)a (targeted value) | t1/2 (h) (targeted value) | AUC0-24h (μg/ml·h) |
---|---|---|---|
Daptomycin | 11.79 ± 0.22 (11.3) | 8.21 (8) | 199.77 |
Moxifloxacin | 2.52 ± 0.14 (2.5) | 12.13 (12.5) | 44.15 |
Vancomycin | 22.6 ± 0.17 (20) | 5.91 (6) | 192.88 |
Rifampin | 3.82 ± 1.21 (3.5) | 3.56 (3) | 19.65 |
Clarithromycin | 1.15 ± 0.6 (1) | 3.91 (3.5) | 6.53 |
Data are means ± standard deviations.