TABLE 4.
Binding parameters of interactions of selected peptides with heparin by real-time SPR
| Peptide | Kd (M)a | Correlation coefficient of linear regression |
|---|---|---|
| SB007-pyrE | 46.7 × 10−9 | 0.87 |
| SB105 | 57.6 × 10−9 | 0.89 |
| SB105-A10b | 15.6 × 10−9 | 0.86 |
| 87.6 × 10−9 | 0.81 | |
| SB056-dim5 | Not determinable | Not determinable |
| SB047 | Not determinable | Not determinable |
a
The Kd at equilibrium was calculated by Scatchard plot analysis of the data from the saturation curves reported in Fig. 4B, C, and D.
b
The Kd values for the two-component binding curve of SB105-A10 are reported.