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. 2010 Jun 17;109(3):820–829. doi: 10.1152/japplphysiol.91430.2008

Fig. 1.

Fig. 1.

Effect of hyperbaric oxygen (HBO) on the field excitatory postsynaptic potential (fEPSP) in CA1 neurons during electrical stimulation of Schaffer collaterals. A: the fEPSP response in CA1 neurons during HBO was variable. Although a 16-min exposure to 2.84 ATA O2 appeared to stimulate the fEPSP, no significance was found in the averaged response to 2.84 ATA O2 exposure (n = 9). B: similar to the response to 2.84 ATA O2, the fEPSP was variable and not significantly affected during a 16-min exposure to 4.54 ATA O2 (n = 7). C: plotting the individual fEPSP experiments before (control, CON; t = 0 min) and during the exposure (HBO; t = 32 min) to either 2.84 ATA O2 (○) or 4.54 ATA O2 (▴) revealed that HBO stimulated the fEPSP in a subset of experiments (n = 4/16). Raw data traces are shown from experiments where HBO exposure stimulated the fEPSP ≥150% or where HBO did not significantly affect the fEPSP. The arrowheads denote the stimulus artifact removed from trace. D: the response to HBO could be divided into 2 groups: stimulation (●) or no effect (▿); however, the predominant fEPSP response to HBO was no effect (n = 12/16).