Figure 6.

Piracetam improves cerebral hypoperfusion-induced deficits in learning and memory. Rats were treated for 30 days with piracetam 600mg/kg per day after ligature of bilateral carotid arteries. The Sham-operated group was only treated with saline without induction of hypoperfusion. The Morris water maze was performed with four trials per day during 5 days for the acquisition test (A), and performed with four trials on day 6 without the platform retention test (n = 10 ± SEM) (B). Representative examples of typical swim-tracking pathways in probe trial on training day 6 no platform (C). (n = 10 ± SEM). Data are reproduced from He et al. (2008) with permission. *p < 0,01 vs. Sham-operated, and #p < 0.05 vs. control hypoperfusion. Tukey's test following a repeated ANOVA.