Effects of the antidepressant drugs nomifensine (nomifen, a DA reuptake inhibitor, 2.5 mg/kg), desipramine (desipr, a NE reuptake inhibitor, 10 mg/kg), and sertraline (sertral, an SSRI, 10 mg/kg) on FST behaviors in postpartum vs. virgin control female rats tested on postpartum day 2. Rats were not pre-exposed to the FST; parturition served as the “inescapable stressor.” Vehicle or drug was administered subchronically (24, 5 and 1 hr before the FST). Locomotor activity was assessed for 5 min, approximately 15 min after the FST. Each bar is the mean + 1 S.E.M., N=5-13 control rats or 8-19 postpartum rats. *significantly different from vehicle-treated group, p≤0.05.