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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: Pharmacol Biochem Behav. 2010 Jul 1;96(4):402–412. doi: 10.1016/j.pbb.2010.06.012

Figure 5.

Figure 5

Effects of subchronic (24-hr) vs. chronic (2-week) administration of the antidepressant drugs desipramine (10 mg/kg) or sertraline (10 or 20 mg/kg) on FST behaviors in postpartum vs. virgin control female rats tested on postpartum day 2. The 10 mg/kg dose of sertraline administered chronically (during pregnancy) caused labor complications and pup death, so the 20 mg/kg dose of sertraline was only tested subchronically. Rats were pre-exposed the FST on pregnancy day 12, to elevate postpartum immobility scores. Each bar is the mean + 1 S.E.M., N=8-13 control rats or 5-7 postpartum rats. *significantly different from vehicle-treated rats within same treatment regimen, p≤0.05.