Fig. 3.

Action potential generation was inhibited by selective sst₄ stimulation in isolated ganglion cells. A: example of a current-clamp recording, in which injection of depolarizing current (150 pA, timing per trace shown below) generated repetitive action potentials in an isolated ganglion cell. The cell's resting potential was set near −60 mV with continuous injection of hyperpolarizing current. B: following administration of L-803,087 (10 nM) for 30 s, the frequency of action potentials was reduced in the same cell. C: continued treatment with L-803,087 inhibited the repetitive action potentials all together.