Table 1.
Summary of injection experiments
Injection Site |
Stimulus Location |
Strength of Inactivation |
Fixation Offset |
Change in Bias |
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Subject | Injection No. | Injection Volume, μl | Injection Depth, mm | H,° | V,° | H,° | V,° | S1 | S2 | H,° | V,° | Pursuit | Saccade | Button |
V | 1† | 0.5 | 2.70 | −3.7 | −1.6 | −3.5 | −0.3 | 0.83 | 0.71 | 0.08 | 0.03 | 1.47* | 0.72* | 0.51* |
2 | 0.5 | 1.90 | 1.1 | 1.1 | 3.5 | 0.3 | 0.97 | 0.85 | −0.02 | −0.04 | 0.58* | 0.24 | 0.25 | |
3† | 0.5 | 2.50 | 0.6 | −0.1 | 3.5 | 0.3 | 0.91 | 0.67 | −0.11 | −0.01 | 1.27* | 0.74* | 0.34* | |
4 | 0.5 | 2.00 | −4.4 | −0.5 | −3.5 | −0.3 | 0.79 | 0.67 | 0.06 | 0.06 | 1.65* | 0.79* | 0.14 | |
5† | 0.5 | 2.00 | 1.9 | 2.2 | 3.5 | 0.3 | 1.02 | 0.79 | −0.11 | −0.02 | 1.20* | 1.02* | −0.41 | |
6† | 0.5 | 2.05 | 1.5 | 0.5 | 3.5 | 0.3 | 0.97 | 0.68 | −0.01 | −0.04 | 2.04* | 0.34* | 0.00 | |
7 | 0.5 | 1.80 | −4.5 | −0.3 | −3.5 | −0.3 | 0.84 | 0.65 | 0.10 | 0.01 | 2.33* | 1.18* | 0.28 | |
8 | 0.5 | 2.00 | −2.9 | −0.3 | −3.5 | −0.3 | 0.72 | 0.55 | 0.09 | 0.06 | 2.64* | 1.25* | 0.39* | |
9† | 0.5 | 2.20 | 0.2 | 0.8 | 3.5 | 0.3 | 1.06 | 0.70 | −0.05 | 0 | 1.34* | 0.41* | 0.21 | |
10‡ | 0.5 | 2.10 | −4.8 | 0.5 | −3.5 | −0.3 | 1.09 | 1.11 | 0.03 | 0.03 | −0.05 | 0.20 | −0.43 | |
11 | 0.45 | 2.00 | 4.0 | 0.2 | 7.5 | 0.3 | 0.66 | 0.55 | −0.15 | −0.03 | 2.81* | 1.25* | 0.94* | |
12 | 0.5 | 2.00 | −3.4 | −0.3 | −7.5 | −0.3 | 0.90 | 0.60 | 0 | 0 | 2.02* | 0.79* | 0.12 | |
13 | 0.4 | 2.00 | 4.2 | 0.3 | 7.5 | 0.3 | 0.81 | 0.53 | −0.17 | −0.01 | 2.02* | 0.75* | 0.20 | |
P | 14 | 0.5 | 2.45 | −1.6 | −0.3 | −4.5 | −0.3 | 0.76 | 0.51 | 0.39 | 0.29 | 3.29* | 1.76* | 0.53* |
15 | 0.5 | 2.00 | 4.0 | 0.3 | 4.5 | 0.3 | 0.91 | 0.72 | 0.29 | 0.60 | 1.66* | 2.02* | 0.17 | |
16 | 0.5 | 2.75 | 3.3 | 0.6 | 4.5 | 0.3 | 0.59 | 0.61 | −0.56 | 0.07 | 1.54* | 2.00* | 0.24 | |
17 | 0.25 | 2.25 | −1.7 | −0.4 | −4.5 | −0.3 | 0.62 | 0.58 | 1.11 | 0.30 | 2.71* | 1.73* | 0.45* | |
18‡ | 0.5 | 2.30 | 2.5 | −0.1 | 4.5 | 0.3 | 0.95 | 1.08 | −0.13 | 0 | 0.01 | 0.04 | −0.04 | |
19 | 0.5 | 2.40 | −2.3 | −0.1 | −6.5 | −0.3 | 0.87 | 0.72 | 0 | −0.04 | 0.62* | 1.25* | −0.01 | |
20 | 0.5 | 2.25 | 1.2 | 0.4 | 6.5 | 0.3 | 0.57 | 0.49 | −0.16 | 0.04 | 1.30* | 1.50* | 0.31* |
Summary of injection experiments. The injection site was measured by the mean horizontal (H) and vertical (V) amplitude of evoked saccades at the injection depth. The location of the stimulus targeted by each injection is provided, and the strength of inactivation is given by the peak velocity of saccades to that location shortly after injection (S1) and after data collection (S2), normalized to pre-injection saccades. The fixation offset indicates the mean displacement in eye position during fixation caused by SC inactivation.
, the change in bias was statistically significant at the 0.05 level;
, the injection site was measured from the same site and depth on the previous day due to failure to evoke saccades with the injectrode;
, saline was injected instead of muscimol.