Table 1.

Transgenic rescue of thrombocytosis and hepatomegaly in Urah^plt2/plt2 mice

Genotype	n	Body weight, g	Liver weight, g	Liver/body weight ratio	Platelets, 109/L
plt2/plt2	15	22.3 ± 2.8	1.47 ± 0.24	0.066 ± 0.007*	1,913 ± 309*
plt2/plt2 Tg	14	22.3 ± 3.5	1.15 ± 0.19	0.052 ± 0.004†	1,201 ± 138†
plt2/+	11	21.9 ± 3.7	1.08 ± 0.23	0.049 ± 0.005	1,257 ± 176
plt2/+ Tg	10	21.6 ± 2.7	1.08 ± 0.18	0.050 ± 0.007	1,164 ± 278
+/+	13	21.6 ± 3.7	1.08 ± 0.22	0.050 ± 0.007	1,113 ± 197
+/+ Tg	8	20.0 ± 3.2	0.98 ± 0.14	0.049 ± 0.003	1,109 ± 124

 Tg, presence of the WT Urah^long transgene; n, number of mice analyzed.

*P < 10⁻⁴ for comparison of plt2/plt2 with +/+ mice.

^†P < 10⁻⁴ for comparison of plt2/plt2 Tg with plt2/plt2 mice.