CoREST and REST target genes in NSCs and other neural cell types. We identified 7,033 total CoREST targets and 5,042 total REST targets in neural cell species through ChIP-chip experiments. We compared profiles of CoREST and REST target genes in NSCs with those at specific developmental stages and in individual neural cell types, including neuronal subtypes (cholinergic, medium spiny, GABAergic, and glutamatergic neurons), oligodendrocyte (OL) lineage species, neural progenitors/precursors (neuronal-oligodendrocyte progenitors, radial glia, and OL precursors), and astrocytes (21, 22). (A) Percentages of the total number of CoREST or REST target genes present in all neural species that are targets within NSCs. (B and C) Comparative profiles of CoREST (B) and REST (C) target genes in NSCs and other neural cell types.