Table 1.

Genes involved in stem cell maintenance, epigenetic regulatory networks, and disease states are CoREST and REST targets in NSCs

	Plurinet, %	Oct4/Sox2/Nanog, %	Nanog, %	Oct4, %	Sox2, %	Glioblastoma, %	Huntington's disease, %	REST-miRNA network, %
	(225)	(408)	(4,085)	(3,309)	(1,113)	(192)	(37)	(16)
CoREST (1,820)	22 (49)**	19 (79)*	16 (671)*	17 (574)*	19 (208)*	15 (29)*	19 (7)	19 (3)
REST (322)	2 (4)	2 (8)	2 (88)	3 (86)*	2 (25)	2 (3)	22 (8)*	0 (0)

Shown are genes involved in pluripotency, including “Plurinet” (23) and composite and individual Oct4/Sox2/Nanog networks (24), neurological diseases (glioblastoma, ref. 25; and Huntington's, ref. 27), and REST-miRNA networks (28). Percentage refers to the proportion of genes within a particular network that are CoREST or REST NSC targets, and the numbers in parentheses represent the actual number of genes.

*P < 0.001.