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. 2010 Sep 23;6(9):e1001131. doi: 10.1371/journal.pgen.1001131

Figure 5. Power of the statistics for testing interaction between two unlinked loci.

Figure 5

(A) The power of the test statistic Inline graphic, the “fast-epistasis” in PLINK and logistic regression analysis for testing interaction between two unlinked loci as a function of traditional odds-ratio Inline graphic under a two-locus recessiveInline graphicrecessive disease model, where the number of individuals in both the case and control groups is 2,000, the significance level is 0.001, and the odds-ratios at two loci were Inline graphic. (B) The power of the test statistic Inline graphic, the “fast-epistasis” in PLINK and logistic regression analysis for testing interaction between two unlinked loci as a function of traditional odds-ratio Inline graphic under a two-locus dominantInline graphicdominant disease model, where the number of individuals in both the case and control groups is 1,000, the significance level is 0.001, and the odds-ratios at two loci were Inline graphic. (C) The power of the test statistic Inline graphic, the “fast-epistasis” in PLINK and logistic regression analysis for testing interaction between two unlinked loci as a function of traditional odds-ratio Inline graphic under a two-locus additiveInline graphicadditive disease model, where the number of individuals in both the case and control groups is 1,000, the significance level is 0.001, and the odds-ratios at two loci were Inline graphic.