Table 2. Correlation results between cortical thickness of eight neocortical ROIs and total hippocampal volume in all ADNI participants (n = 724).
Regions of Interest | HV | CMF | ERC | IPL | ITG | ISC | LOC | MOF | TP |
HV | 1 | 0.29 | 0.66 | 0.32 | 0.45 | 0.36 | 0.28 | 0.41 | 0.51 |
CMF | 1 | 0.38 | 0.79 | 0.65 | 0.60 | 0.64 | 0.43 | 0.42 | |
ERC | 1 | 0.43 | 0.63 | 0.43 | 0.36 | 0.44 | 0.72 | ||
IPL | 1 | 0.74 | 0.67 | 0.74 | 0.44 | 0.44 | |||
ITG | 1 | 0.63 | 0.64 | 0.51 | 0.64 | ||||
ISC | 1 | 0.52 | 0.50 | 0.43 | |||||
LOC | 1 | 0.38 | 0.38 | ||||||
MOF | 1 | 0.48 | |||||||
TP | 1 |
Spearman's rank correlation coefficients listed, all p-values significant at <0.0001. All analyses included age, gender, education, and APOE-ε4 carrier status as co-variates. HV = Hippocampal volume, CMF = Caudal portion of middle frontal gyrus thickness, ERC = Entorhinal cortex thickness, IPL = Inferior parietal lobule thickness, ITG = Inferior temporal gyrus thickness, ISC = Isthmus portion of cingulate cortex thickness, LOC = Lateral portion of occipital cortex thickness, MOF = Medial portion of orbital frontal cortex thickness, TP = Temporal pole thickness.