Table 3.
Fatty acid | Healthy subjects | Type-2 diabetic patients | ||
---|---|---|---|---|
mol% | nmol/mg protein | mol% | nmol/mg protein | |
16:0 | 12.3 ± 0.5 | 325.7 ± 15.7 | 13.8 ± 0.4 | 288.4 ± 15.5 |
16:1n-7 | 2.5 ± 0.4 | 63.7 ± 7.8 | 2.7 ± 0.4 | 56.2 ± 9.0 |
16:1n-9 | 0.3 ± 0.1 | 7.4 ± 2.1 | 0.4 ± 0.1 | 8.7 ± 1.8 |
18:0 | 1.0 ± 0.1 | 23.3 ± 2.2 | 1.0 ± 0.1 | 18.9 ± 2.5 |
18:1n-7 | 1.1 ± 0.2 | 26.0 ± 4.8 | 0.9 ± 0.3 | 18.2 ± 5.4 |
18:1n-9 | 20.7 ± 0.9 | 500.5 ± 22.1 | 22.5 ± 0.8 | 430.5 ± 19.0 |
18:2n-6 | 52.4 ± 1.4 | 1295.5 ± 102.6 | 46.6 ± 1.4** | 909.3 ± 72.0** |
18:3n-3 | 0.4 ± 0.1 | 11.2 ± 2.0 | 0.5 ± 0.1 | 8.8 ± 2.3 |
18:3n-6 | 0.7 ± 0.2 | 18.3 ± 4.8 | 0.7 ± 0.2 | 13.4 ± 3.2 |
20:3n-6 | 0.7 ± 0.1 | 16.6 ± 1.7 | 0.8 ± 0.1 | 15.2 ± 2.2 |
20:4n-6 | 6.0 ± 0.5 | 140.7 ± 20.6 | 8.6 ± 0.7** | 151.8 ± 9.5 |
20:5n-3 | 1.2 ± 0.3 | 26.9 ± 5.9 | 0.9 ± 0.2 | 15.5 ± 2.6 |
22:6n-3 | 0.7 ± 0.1 | 13.6 ± 1.9 | 0.6 ± 0.1 | 10.0 ± 1.7 |
SFA | 13.3 ± 0.6 | 350.5 ± 17.6 | 14.8 ± 0.3* | 308.4 ± 16.6 |
MUFA | 24.5 ± 1.0 | 598.5 ± 22.0 | 26.6 ± 0.6 | 514.2 ± 19.4* |
PUFA | 62.2 ± 1.4 | 1523.2 ± 125.4 | 58.6 ± 0.8* | 1124.2 ± 77.0* |
Values expressed as mole percent of main fatty acids and nmol/mg protein. are means ± S.E.M. of at least six subjects per group.
p ≤ 0.05 and
p ≤ 0.01 compared with LDL from healthy subjects.
MUFA. monounsaturated fatty acids; PUFA. polyunsaturated fatty acids; SFA. saturated fatty acids.