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. 2010 Sep 23;5(9):e12957. doi: 10.1371/journal.pone.0012957

Table 2. Anti-microbial serological markers in patients with chronic liver diseases and healthy controls.

ASCA Anti-OMP Plus™
Number IgA and/or IgG IgA
Liver cirrhosis with various etiology 286 110 (38.5%)* 179 (62.6%)*
Chronic HCV without cirrhosis 124 11 (8.9%)# 3 (2.4%)#
Autoimmune liver diseases without cirrhosis 266 59 (22.2%) 44 (16.5%)
PBC 153 31 (20.3%) 26 (17.0%)
PSC 59 18 (30.5%)&,φ 9 (15.3%)
AIH 54 10 (18.5%) 9 (16.7%)
Healthy controls 100 16 (16%) 20 (20%)

AIH = autoimmune hepatitis, HCV = viral hepatitis C, PBC = primary biliary cirrhosis, PSC = primary sclerosing cholangitis.

*p<0.001 between liver cirrhosis and chronic HCV, autoimmune liver diseases, healthy controls.

#

p<0.001 between chronic HCV patients and autoimmune liver diseases, healthy controls.

&

p = 0.04 between PSC and healthy controls.

φ

p<0.001 between PSC and chronic HCV.

p<0.01 between PSC and chronic HCV.

by using Fisher's exact test or χ2-test with Yates correction if appropriate.