Table 2. Anti-microbial serological markers in patients with chronic liver diseases and healthy controls.
ASCA | Anti-OMP Plus™ | ||
Number | IgA and/or IgG | IgA | |
Liver cirrhosis with various etiology | 286 | 110 (38.5%)* | 179 (62.6%)* |
Chronic HCV without cirrhosis | 124 | 11 (8.9%)# | 3 (2.4%)# |
Autoimmune liver diseases without cirrhosis | 266 | 59 (22.2%) | 44 (16.5%) |
PBC | 153 | 31 (20.3%) | 26 (17.0%) |
PSC | 59 | 18 (30.5%)&,φ | 9 (15.3%)⊥ |
AIH | 54 | 10 (18.5%) | 9 (16.7%) |
Healthy controls | 100 | 16 (16%) | 20 (20%) |
AIH = autoimmune hepatitis, HCV = viral hepatitis C, PBC = primary biliary cirrhosis, PSC = primary sclerosing cholangitis.
*p<0.001 between liver cirrhosis and chronic HCV, autoimmune liver diseases, healthy controls.
p<0.001 between chronic HCV patients and autoimmune liver diseases, healthy controls.
p = 0.04 between PSC and healthy controls.
p<0.001 between PSC and chronic HCV.
p<0.01 between PSC and chronic HCV.
by using Fisher's exact test or χ2-test with Yates correction if appropriate.