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. 2010 Sep 23;5(9):e12961. doi: 10.1371/journal.pone.0012961

Table 1. Correlation between MBP-1 expression and clinicopathological characteristics of breast cancer patients.

Variable Total (%) MBP-1 nuclear immunoreactivity P
Positive (%) Negative (%)
Age (yr)
≤50 51 (29) 15 (23) 36 (32)
>50 126 (71) 51 (77) 75 (68) NS
Tumor size
≤2 cm 68 (38) 28 (42) 40 (36)
>2 cm 109 (62) 38 (58) 71 (64) NS
Node status
negative 85 (48) 44 (67) 41 (37)
positive 92 (52) 22 (23) 70 (63) 0.0002
Tumor grade
1–2 80 (45) 43 (65) 37 (33)
3–4 97 (55) 23 (35) 74 (67) <0.0001
ErbB2
negative 122 (69) 58 (88) 64 (58)
positive 55 (31) 8 (12) 47 (52) <0.0001
ER
negative 39 (26) 15 (59) 24 (25)
positive 112 (74) 41 (61) 71 (75) NS
PG
negative 57 (38) 16 (29) 41 (43)
positive 94 (62) 40 (71) 54 (57) NS
Ki67
negative 33 (19) 19 (29) 14 (13)
positive 144 (81) 47 (71) 97 (87) 0.0096
Recurrences
recurrent 32 (40) 4 (17) 28 (51)
non recurrent 47 (60) 20 (83) 27 (49) 0.0057
Death for disease
Yes 19 (24) 3 (13) 16 (29)
No 60 (76) 21 (87) 39 (71) NS

NOTE: Statistical analyses were done by the Fisher's exact test. A P value of <0.05 was considered significant.

Abbreviations: ER, estrogen receptor; PG, progesterone receptor;

NS, nonsignificant.