. Author manuscript; available in PMC: 2010 Dec 1.

Published in final edited form as: Environ Toxicol. 2010 Dec;25(6):608–621. doi: 10.1002/tox.20621

Table 1.

Mitotic Index and different types of chromosome aberrations, in bone-marrow cells of Swiss-Webster mice exposed to functionalized MWCNT.

Dose (mg/Kg)	Total metaphases Examined	MI%	Chromatid		Chromosome		Fragment	Union	Total SCA	Cells with SCA^a (%)
Dose (mg/Kg)	Total metaphases Examined	MI%	Gap	Break	Gap	Break	Fragment	Union	Total SCA	Cells with SCA^a (%)
Saline (0.9%)	500	11.98	3	2	2	1	1	1	10	2.0 ± 0.9^a
1% Tween-20	500	11.5	2	2	3	2	2	1	12	2.4 ± 0.6^a
Saline + Tween	500	10.06	3	2	5	3	3	2	18	3.6 + 0.9^a
Carbon Black (CB)	500	7.12	6	3	7	2	2	2	22	4.4 ± 1.73^a
0.25	500	4.5	7	3	8	4	5	3	30	6.0 ± 3.7^a
0.5	500	2.88	9	6	8	3	15	5	46	9.2 ± 1.5^a
0.75	500	2.12	16	6	13	10	21	4	70	14.0 ± 4.2^a

One hundred cells were analyzed per animal, to a total of 500 metaphase cells/treatment, CB: carbon black, SCA: structural chromosomal aberrations; MI: mitotic index

Standard Deviation (S.D)