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. 2010 Mar 9;136(11):1697–1707. doi: 10.1007/s00432-010-0828-5

Table 4.

Expression levels of HIF-1α and MDR1 mRNA under normoxic and hypoxic conditions in human colon carcinoma cells

Experimental group HCT-116 HT-29 LoVo SW480
AHIF-1α/AGAPDH N 0.4901 ± 0.0472 0.4872 ± 0.0592 0.4824 ± 0.0325 0.4941 ± 0.0687
H 0.9989 ± 0.0312* 0.9968 ± 0.0618* 0.9978 ± 0.0721* 0.9944 ± 0.0576*
AMDR1/AGAPDH N 0.3932 ± 0.0295 0.3952 ± 0.0793 0.3937 ± 0.0671 0.3961 ± 0.0990
H 0.9909 ± 0.0562** 0.9954 ± 0.0388** 0.9972 ± 0.0422** 0.9934 ± 0.0764**

Note N Normoxia; H Hypoxia

*  P < 0.01, analysis of HIF-1α mRNA expression of the same type of cell under normoxic and hypoxic culture conditions, compared with normoxia group; **  P < 0.01, analysis of MDR1 mRNA expression of the same type of cell under normoxic and hypoxic culture conditions, compared with normoxia group