Table 4.
AUC (95% CI) | OR (95% CI) | P-value | |
---|---|---|---|
Model 1 (M1) | |||
ACTH ≤ 233 nM/L | 0.875 (0.774 to 0.942) | 9.192 (2.466 to 34.265) | 0.001 |
Cortisol baseline ≥ 450 nM/L | 4.279 (1.007 to 18.181) | 0.049 | |
Sepsis score >7 | 5.371 (1.567 to 18.404) | 0.007 | |
Model 2 (M2) | |||
ACTH ≤ 233 nM/L | 0.903 (0.808 to 0.960) | 21.16 (4.252 to 105.307) | 0.0002 |
Cortisol baseline ≥ 450 nM/L | 8.81 (1.616 to 48.037) | 0.012 | |
Procalcitonin (PCT) >2 ng/mL | 28.558 (4.393 to 185.636) | 0.0004 | |
Model 3 (M3) | |||
ACTH ≤ 233 nM/L | 0.805 (0.693 to 0.890) | 9.125 (2.667 to 31.218) | 0.0004 |
Cortisol baseline ≥ 450 nM/L | 7.457 (1.89 to 29.426) | 0.004 | |
Model 4 (M4) | |||
Procalcitonin (PCT) >2 ng/mL | 0.726 (0.607 to 0.826) | 16.889 (3.523 to 80.959) | 0.0004 |
Model 5 (M5) | |||
Sepsis score >7 | 0.727 (0.607 to 0.827) | 6.481 (2.34 to 17.952) | 0.0003 |
ACTH, adreno corticotropic hormone; AUC, area under the receiver operating characteristic curve; CI, confidence interval; OR: odds ratio; PCT, procalcitonin.