Table 2.

Predictors for functional outcome

	Good outcome (mRS ≤ 2)
	Exp(Coef)	95% CI	P-value
Univariate
Age	0.834	0.794 to 0.872	< 0.0001
SEX (female)	1.265	0.554 to 1.864	0.57645
Hospital LOS	0.759	0.281 to 0.866	0.04397
Length of ventilation	0.410	0.113 to 0.641	0.01202
Length of ventilation (per increasing day)	0.974	0.913 to 1.061	0.09441
TISS-28 on Day 1
< 21	2.746	1.935 to 4.391	0.00666
20 to 40	1.273	0.764 to 1.812	0.21932
> 40	0.715	0.621 to 0.944	0.00181
TISS-28 at discharge
< 21	2.187	1.453 to 3.812	0.01215
20 to 40	1.234	0.218 to 2.187	0.23156
> 40	0.711	0.451 to 0.857	0.00017
Ischemia	0.724	0.485 to 0.932	0.04275
ICH	0.743	0.573 to 0.935	0.02046
SAH	0.636	0.273 to 1.198	0.63532
Meningoencephalitis	1.412	0.996 to 3.238	0.12432
Epilepsy	1.433	0.233 to 2.346	0.73255
GBS/MG	3.623	1.124 to 13.327	0.00145
Neurodeg./Encephalopathy	0.680	0.274 to 1.019	0.05723
Neoplasm	0.692	0.371 to 0.856	0.00039
Intoxication	5.809	1.832 to 7.483	0.03881
Multivariate
Age	0.786	0.435 to 0.823	0.00245
Hospital LOS	0.509	0.272 to 1.279	0.17647
Length of ventilation	0.681	0.475 to 0.912	0.00354
TISS-28 on Day 1 > 40	0.815	0.578 to 0.931	0.00187
Ischemia	0.345	0.245 to 1.101	0.11458
ICH	0.643	0.218 to 0.877	0.03874
GBS/MG	2.215	2.006 TO 3.214	0.03329
Neurodeg./Encephalopathy	0.705	0.297 to 1.354	0.15478
Neoplasm	0.687	0.354 to 0.934	0.04875
Intoxication	1.399	0.964 to 2.648	0.27261

Univariate and multivariate regression analysis for parameters predicting a good functional outcome (mRS 0 to 2) one year after neurocritical care. Analysis of all patients receiving specialized neurocritical care (n = 666). Parameters that reached significance (P < 0.05) are expressed in bold. Parameters that showed a statistical trend (P < 0.1) in the univariate analysis are expressed in italics.

Abbreviations: CI, confidence interval; LOS, length of stay; ICH, intracranial hemorrhage; SAH, subarachnoid hemorrhage; GBS, Guillain-Barré syndrome; MG, myasthenia gravis; Neurodeg, neurodegenerative disease