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. 2010 Aug 3;14(4):R145. doi: 10.1186/cc9213

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Copyright ©2010 Schouten et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Survival in antibiotic treated pneumococcal pneumonia. Survival of wild-type mice (open square, dotted line white, n = 10) and mice heterozygous (light grey squares and line white, n = 10) or homozygous (dark grey squares and line white, n = 8) for the factor V Leiden mutation treated intraperitoneally with ceftriaxone 24 hours after induction of pneumococcal pneumonia. * indicates statistical significance for the comparison between homozygous factor V Leiden and wild-type mice (P < 0.05 log rank test), ** indicates statistical significance for the comparison between homozygous and heterozygous factor V Leiden mice (P < 0.01 log rank test).