Table 5.
Clinical outcomes in the three intervention groups
| CVP group n = 45 |
SV group n = 45 |
SV & DPX group n = 45 |
P | |
|---|---|---|---|---|
| Complications (number of patients, %) |
30 (67%) | 26 (58%) | 31 (69%) | 0.51 |
| Cardiac complications (number of patients, %) | 4 (9%) | 3 (7%) | 3 (7%) | 0.90 |
| Infectious complications (number of patients, %) | 29 (64%) | 24 (53%) | 28 (62%) | 0.52 |
| Other complications (number of patients, %) | 10 (22%) | 14 (31%) | 12 (27%) | 0.63 |
| Acute kidney injury within 7 days of surgery | 10 (22%) | 3 (7%) | 4 (9%) | 0.055* |
| Critical care free days within 28 days of surgery | 24 (21-26) | 24 (21-26) | 26 (21-27) | 0.45 |
| Duration of hospital stay (days) | 15 (10-26) | 14 (11-26) | 16 (11-28) | 0.73 |
| Hospital mortality (%) | 6 (13%) | 5 (11%) | 4 (9%) | 0.45 |
Data presented as median (interquartile range) or absolute values (%). Note: A number of patients developed more than one complication. Acute kidney injury at seven days not included in 28 day complication outcome.
*Significant difference in incidence of acute kidney injury between pooled SV and SV & DPX groups and the CVP group (P = 0.03, post hoc analysis). CVP, central venous pressure; DPX, dopexamine; SV, stroke volume.