Table 4.
Cut-off values for CPA-ROSC and diagnostic accuracy
| CPA-ROSC | Sensitivity | Specificity | Positive predictive value | Negative predictive value | Accuracy (%) |
|---|---|---|---|---|---|
| Hypothermia group | |||||
| 18 minutes | 37 (28 to 46) | 91 (86 to 96) | 73 (65 to 81) | 69 (60 to 78) | 70 |
| 25 minutes | 60 (51 to 69) | 84 (77 to 91) | 70 (61 to 79) | 77 (69 to 85) | 74 |
| 29 minutes | 70 (61 to 79) | 79 (71 to 87) | 68 (59 to 77) | 80 (73 to 87) | 75 |
| 34 minutes | 79 (71 to 87) | 70 (61 to 79) | 63 (54 to 72) | 84 (77 to 91) | 74 |
| 45 minutes | 93 (88 to 98) | 40 (31 to 49) | 50 (41 to 59) | 90 (84 to 96) | 61 |
| 65 minutes | 100 | 4 (1 to 8) | 40 (31 to 49) | 100 | 42 |
| Normothermia group | |||||
| 13 minutes | 73 (68 to 78) | 95 (92 to 98) | 71 (66 to 76) | 96 (94 to 98) | 92 |
| 15 minutes | 85 (81 to 89) | 94 (91 to 97) | 69 (64 to 74) | 98 (96 to 99) | 93 |
| 18 minutes | 90 (87 to 93) | 91 (88 to 94) | 62 (56 to 68) | 98 (96 to 99) | 91 |
| 20 minutes | 92 (89 to 95) | 88 (84 to 92) | 55 (49 to 61) | 99 (98 to 99) | 89 |
| 45 minutes | 100 | 49 (43 to 55) | 24 (19 to 29) | 100 | 56 |
Data presented as mean (95% confidence interval) (%). Time interval from collapse to return of spontaneous circulation (CPA-ROSC) cut-off value of 29 minutes in the hypothermia group and 15 minutes in the normothermia group had the highest combined sensitivity and specificity, with accuracies of 75.4% and 92.8%, respectively.