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VDR binding, histone H1 gene cluster, selection, and rs10946808. (A) Enrichment of VDR binding intervals in histone HIST1 gene cluster on chromosome 6p21-22 (chr6: 25,900,000–28,100,000). (B) The region chr6: 26,300,001–26,400,000 reported as showing evidnce of selection includes rs10946808 located 3′ of HIST1H1D. (C) Data from the Human Genome Diversity Project show rs10946808 has a higher minor allele frequency in Asians.
