Skip to main content
. Author manuscript; available in PMC: 2011 Sep 23.
Published in final edited form as: J Med Chem. 2010 Sep 23;53(18):6699–6705. doi: 10.1021/jm100846r

Table 3.

Activity of 2–4 against Hep3B and Hep3B-VIN

GI50 (µM)
Hep3B Hep3B-VIN Hep3B/Hep3B-VIN
2 47.57 1.57 30
3 7.31 0.35 21
4 6.09 0.72 8.5
paclitaxel 0.0004 16.17 -
vincristine 0.0029 6.86 -