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Tau-immunoreactive (AT8) NFTs, astrocytic tangles and neuropil neurites are found in many subcortical nuclei including the substantia nigra (A, case 3, original magnification x350) and nucleus basalis of Meynert (B, case 3, original magnification x350). NFTs are also abundant in the olfactory bulb (C, case 2, Bielschowsky silver method, original magnification x150) and thalamus (case 1, original magnification x350, AT8 immunostain counterstained with cresyl violet).
