Table 3. Neurodevelopmental and Magnetic Resonance Imaging Evaluations at Age One-Year According to Categories of Integrated Cerebral Oxygen Saturation (rSO₂) ≤ 45%.

Variable	Integrated rSO2 ≤ 45% (min%)
	0	0.3 – 39	60 – 383	P
Bayley Scales of Infant Development	(N=66)	(N=12)	(N=11)
Psychomotor Development Index	88 ± 16	85 ± 20	86 ± 17	0.81
Mental Development Index	94 ± 11	91 ± 17	96 ±10	0.41
Neurologic Examination	(N=62)	(N=12)	(N=10)
Abnormal neurologic examination, n (%)	37 (60)	8 (67)	5 (50)	0.72
Head circumference, Z-score	–0.02 ± 1.04	0.04 ± 0.86	–0.16 ± 1.10	0.89
Magnetic Resonance Imaging, Qualitative	(N=30)	(N=6)	(N=4)
Brain hemosiderin, n (%)	9 (30)	3 (50)	2 (50)	0.46
Focal stroke	1 (3)	0	0	1.0
Periventricular leukomalacia	2 (7)	0	0	1.0
Magnetic Resonance Imaging, Quantitative (volume in mL)	(N=30)	(N=6)	(N=4)
Gray matter	622 ± 62	606 ± 25	579 ± 55	0.49
Subcortical gray matter	32 ± 11	35 ± 8	43 ± 9	0.02
Myelinated white matter	81 ± 36	80 ± 31	75 ± 26	0.69
Unmyelinated white matter	177 ± 41	184 ± 57	148 ± 27	0.38
Cerebrospinal fluid	99 ± 36	101 ± 29	79 ± 10	0.57
Brain	912 ± 94	906 ± 70	844 ± 99	0.50
Cerebrum	811 ± 86	808 ± 66	748 ± 86	0.47
Cerebellum	101 ± 11	98 ± 9	96 ± 13	0.87

Values are expressed as mean ± standard deviation. P values are determined by analysis of variance for continuous variables and Fisher's exact test for categorical variables. P values for Bayley Scales also adjust for social class, and P values for quantitative magnetic resonance imaging variables also adjust for age at magnetic resonance imaging evaluation.