Table 5. Effects of Cerebral Oxygen Saturation (rSO2) Variables on Hemosiderin.
| Hemosiderin (N = 40*) Logistic Regression Odds Ratio (P value) |
|||
|---|---|---|---|
| rSO2 Predictor Variable | Unadjusted | Adjusting for Age ≤ 30 Days | Adjusting for Diagnosis Group |
| Integrated rSO2 ≤ 45% (min%) | |||
| 0 | 1 | 1 | 1 |
| 0.3-39 | 2.3 (0.35) | 2.5 (0.38) | 2.9 (0.31) |
| 60-383 | 2.3 (0.43) | 10.1 (0.12) | 10.2 (0.11) |
| Integrated rSO2 ≤ 45% (per min%) | 1.01 (0.15) | 1.02 (0.07) | 1.02 (0.07) |
| Postinduction – 60 min post-CPB | |||
| Average rSO2 (per %) | 0.89 (0.02) | 0.90 (0.054) | 0.89 (0.03) |
| Minimum rSO2 | 0.94 (0.08) | 0.91 (0.04) | 0.91 (0.04) |
| Onset last rewarming – off-CPB | |||
| Average rSO2 | 0.91 (0.009) | 0.93 (0.11) | 0.92 (0.047) |
| Minimum rSO2 | 0.92 (0.01) | 0.94 (0.16) | 0.93 (0.07) |
| Off-CPB − 60 min post-CPB | |||
| Average rSO2 | 0.92 (0.02) | 0.93 (0.04) | 0.92 (0.03) |
| Minimum rSO2 | 0.93 (0.03) | 0.94 (0.06) | 0.93 (0.04) |
| rSO2 10 min after cooling | 0.96 (0.25) | 0.97 (0.47) | 0.97 (0.40) |
| rSO2 Off-CPB | 0.87 (0.003) | 0.88 (0.01) | 0.88 (0.006) |
| rSO2 60 min post-CPB | 0.94 (0.08) | 0.95 (0.16) | 0.94 (0.10) |
Logistic regression models for hemosiderin did not converge when adjusting for both age ≤ 30 days and diagnosis group (TGA, TOF, VSD) due to collinearity of age and diagnosis and small cell counts.
*
N = 40, except N = 39 for off CPB − 60 min post-CPB and 60 min post-CPB regressions.