Table 2.
subset | n | Age* +/− (SD) | % female | p-value (gender ratio) | OR (95% CI) |
---|---|---|---|---|---|
LOAD | 528 | 72.2 (6.2) | 63.8 | 0.503 | 1.1 (0.85–1.4) |
CC | 524 | 73.7 (7.2) | 61.8 | ||
Dep+ | 274 | na | 71.1 | 0.002 | 1.6 (1.2–2.3) |
Dep − | 778 | na | 59.9 | ||
DAD | 207 | 71.2 (6.1)** | 68.4 | 0.090 | 1.4 (0.95–2.1) |
LOAD (no DAD) | 321 | 72.5 (6.1) | 60.6 | ||
LOD | 67 | na | 78.5 | 0.003 | 2.5 (1.3–4.6) |
CC (no LOD) | 457 | na | 59.4 | ||
Total | 1052 | na | 62.8 | na | na |
LOAD = Late-Onset Alzheimer Disease
CC = Cognitive Controls
Dep+ = Any Depression with a late in life onset (i.e. DAD + LLD)
Dep− = No History of Depression
DAD = Depression of Alzheimer Disease
LOD = Late-Onset Depression
Age* = Age-at-onset for those with LOAD, and age-at-exam for cognitive controls
DAD cases are significantly younger than LOAD (not DAD) cases p=0.017.