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. Author manuscript; available in PMC: 2010 Sep 24.
Published in final edited form as: J Proteome Res. 2005 Jul–Aug;4(4):1397–1402. doi: 10.1021/pr050077s

Figure 5.

Figure 5

Scheme of the structure of the GPCRs A2A, D2, and D1 and the NR1-1 subunit of the ligand-gated ion channel NMDA receptor. The acidic epitopes of both the A2A and D1 receptors (dark red) are localized in an electronegative domain (light red) of their characteristic long electronegative C termini. The basic epitope of the D2 receptor (dark blue) is localized in an electropositive domain (light blue) of its characteristic long third intracellular loop. The basic epitope of the NR1-1 subunit (dark blue) is localized in an electropositive domain (light blue) of its long electropositive C terminus. Intramembrane domains are shown in green.