Fig. 1.

In isogenic C57BL/6 mice, weanling weight was inversely proportional to litter size (a; 57 litters, R² = 0.9). Male and female mice had normally distributed weanling weights (b; 334 mice, W = 0.99). Neonatal macrosomia was defined by a weight greater than the 90th percentile on postnatal day 20. Weanling (c) and adult weights (d) were measured on postnatal day 20 and at 20 weeks, respectively. ** p < 0.01 versus control by t test.