Table 2.
Results from adjusted logistic regression models stratified by paraquat exposure and age of onset
| Genotype | Paraquat exposure – cases/controls, OR (95% CI)1 |
|||
|---|---|---|---|---|
| low/no | high | |||
| 259/259 or 259/X | 106/131 | 0.77 (0.51–1.15) | 72/49 | 1.35 (0.74–2.46) |
| vs. X/X | 104/105 | 51/51 | ||
| 263/263 or 263/X | 31/29 | 1.22 (0.68–2.18) | 18/13 | 1.45 (0.59–3.59) |
| vs. X/X | 179/207 | 105/87 | ||
| Age of onset – cases/controls, OR (95% CI)2 | ||||||||
|---|---|---|---|---|---|---|---|---|
| ≤68 years | >68 years | ≤68 years | >68 years | |||||
| 259/259 or 259/X | 41/66 | 0.67 (0.36–1.24) | 65/65 | 0.89 (0.53–1.51) | 37/26 | 1.96 (0.81–4.76) | 35/23 | 0.87 (0.37–2.06) |
| vs. X/X | 47/50 | 57/55 | 19/26 | 32/25 | ||||
| 263/263 or 263/X | 15/13 | 1.68 (0.69–4.08) | 16/16 | 0.89 (0.41–1.93) | 9/4 | 3.15 (0.74–13.37) | 9/9 | 0.84 (0.27–2.62) |
| vs. X/X | 73/103 | 106/104 | 47/48 | 58/39 | ||||
X/X represents any other genotype.
1
Adjusted for age (continuous), sex, education (<12, 12 or >12 years), race (White/non-White), smoking status (former, current or never), and family history (positive/negative in a first-degree relative).
2
Adjusted for age (continuous), sex, and smoking status (former, current or never).