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. 2010 Apr 30;47(6):519–530. doi: 10.1159/000313879

Fig. 8.

Fig. 8

Effects of myrAkt on nLDL- and oxLDL-induced apoptosis in wild type EPC. a Effects of Ad-DLE1 (control transduction) and Admiralty (constitutively active Akt transduction) on p-Akt, total Akt, p-GSK3α, total GSK3α and β-actin expression in wild-type EPC. b EPC cultures, transducer with either Ad-DLE1 (control; empty vector) or Ad-myrAkt (constitutively active Akt) were exposed to nLDL (10 μg/ml) or oxLDL (10 μg/ml), or oxLDL (10 μg/ml) in serum-free medium. Apoptosis was determined by TUNEL staining. Data are expressed as the percentage of TUNEL positive cells with respect to the total number of cells (DAPI staining) per high power field. Data are presented as mean ± SD, n = 3;+ p < 0.05 oxLDL versus nLDL or control; * p < 0.05 Ad-myrAkt oxLDL versus Ad-DLE1 oxLDL.