Figure 2. Effect of fasudil on extensor digitalis longorum (EDL) and soleus muscle force:

At 25 weeks of age, in vitro muscle function tests were performed on EDL (A, B, E, F) and soleus (C, D, G, H) muscles to determine the affect of fasudil treatment on muscle force in C57BL6 (B, F, D, H) and SJL/J (A, E, C, G) mice. Shown are the graphs for maximal force (MF) (mN) (A–D) and specific force (SF) (kN/m²) (E–H) for soleus and EDL of each strain. Treatment groups of each strain were compared using student's t-test for independent samples. *p = <0.05 by Student's t-test comparisons.