Table 2.
Strategy, IgE results, physician's diagnosis, prevalences, frequencies, probabilities and costs in the twelve possible diagnostics categories, a1 to a12.
| Category (no. obs) | Strategy | Initial IgE test | Physcian's diagnosis | 1Prevalence | Observed frequence | 2Probability (p) | 3Expected category cost (€) | |||
|---|---|---|---|---|---|---|---|---|---|---|
| year 1 | 4year 2 | year 1&2 | ||||||||
| a1 | (9) | no-test | pos | uncertain | 0,55 | 0,09 | 0,050 | 24 | 23 | 47 |
| a2 | (79) | no-test | pos | allergy | 0,55 | 0,81 | 0,446 | 192 | 186 | 377 |
| a3 | (10) | no-test | pos | no-allergy | 0,55 | 0,10 | 0,055 | 26 | 25 | 52 |
| a4 | (21) | no-test | neg | uncertain | 0,45 | 0,22 | 0,099 | 48 | 46 | 94 |
| a5 | (54) | no-test | neg | allergy | 0,45 | 0,56 | 0,252 | 105 | 102 | 206 |
| a6 | (21) | no-test | neg | no-allergy | 0,45 | 0,22 | 0,099 | 13 | 13 | 26 |
| a7 | (1) | test | pos | uncertain | 0,55 | 0,01 | 0,006 | 1 | 0 | 1 |
| a8 | (87) | test | pos | allergy | 0,55 | 0,95 | 0,523 | 232 | 175 | 408 |
| a9 | (4) | test | pos | no-allergy | 0,55 | 0,04 | 0,022 | 12 | 9 | 21 |
| a10 | (3) | test | neg | uncertain | 0,45 | 0,05 | 0,023 | 12 | 12 | 24 |
| a11 | (10) | test | neg | allergy | 0,45 | 0,17 | 0,077 | 6 | 5 | 10 |
| a12 | (45) | test | neg | no-allergy | 0,45 | 0,78 | 0,351 | 51 | 46 | 97 |
1frequence of positive results during screening, i.e. positive results in Phadiatop/Padiatop Infant
2calculated from the prevalence and observed frequence of being in category
3calculated as the sum of costs for medications, physician visits and allergy tests adjusted for observed episodes per patient on pathway as given in Table 1 and probability of being in category.
4costs in 2nd year were discounted to correspond to 1st year (rate:3%)