. Author manuscript; available in PMC: 2010 Sep 25.

Published in final edited form as: J Trauma. 2010 May;68(5):1072–1077. doi: 10.1097/TA.0b013e3181d7a6f2

TABLE 2.

Univariate and Multivariate Analysis of Laboratory Parameters to Predict Presence of TBI on Head CT From Patients in Cohort 1

	No Brain Injury (n = 38)^*	Brain Injury (n = 19) ICP	Univariate^†	Multivariate^‡
Na (mmol/l)	140 ± 2.2	141 ± 3.3	p = 0.40
K (mmol/l)	3.74 ± 0.45	3.35 ± 0.7	p = 0.02	p = 0.8
PT (s)	13 (11.5–15.8)	13 (11.4–18.7)	p = 0.86
PTT (s)	25 (18–52)	28 (19–45)	p = 0.15
Fibrinogen (mg/dl)	263 (157–520)	230 (132–320)	p = 0.04	p = 0.26
Platelets (10³/μl)	295 (183–519)	283 (71–514)	p = 0.50
D-dimer (pg/μ)	688 (150–5000)	5000 (154–5000)	p < 0.001	p = 0.02
MMP9 (pg/ml)	183 (25–686)	170 (25–1300)	p = 0.94
S100β (pg/ml)	100 (100–1250)	100 (100–1260)	p = 0.65
GCS	15 (6–15)	13 (3–15)	p < 0.001	p = 0.08

Na, sodium; K, potassium; PTT, partial thromboplastin time; MMP-9, major metalloproteinase-9; GCS, Glascow Coma Scale.

Mean ± SD or median (range).

^†

Statistical tests: Na and K, student’s t test; all other variables, Wilcoxon rank sum.

^‡

Standard logistic regression using variables with P ≤ 0.05 from univariate analysis.