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. Author manuscript; available in PMC: 2011 Sep 24.
Published in final edited form as: J Mol Biol. 2010 Aug 11;402(3):560–577. doi: 10.1016/j.jmb.2010.08.007

Figure 4. NHR3 mutations impair PKA (RIIα) binding.

Figure 4

(A) ITC for binding of W594A Trx-NHR3 (585-615) to PKA(RIIα). Data numbers presented are averages with standard deviations from two independent runs. Eight μL injections were made at 25°C. Kd and stoichiometry (N) are indicated in the box.

(B) ITC for binding of V604A Trx-NHR3 (585-615) to PKA(RIIα), performed as described in B.

(C) ITC for binding of V601A Trx-NHR3 (585-615) to PKA(RIIα), performed as described in B.