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. Author manuscript; available in PMC: 2011 Mar 23.
Published in final edited form as: Oncogene. 2010 Jul 26;29(38):5241–5253. doi: 10.1038/onc.2010.264

Fig. 8. Sprouty-2 up-regulation increases tumor xenograft growth in BALB/c-nu/nu mice.

Fig. 8

EV or sprouty-2 transfectants were injected into flanks of nude mice (5 mice in each group). Tumor size was measured every week and on day 28 tumors were excised as described in “Materials and Methods”. Significant increases in sprouty-2 transfectant tumor sizes were detected on day 14, 21 and 28 compared to time-matched EV tumors. *p< 0.05, compared to mice injected with EV transfected cells. Inset, sprouty-2 up-regulation significantly increases tumor weight compared to EV tumors (day 28). *p< 0.05, compared with tumors from mice injected with EV transfectants.