. Author manuscript; available in PMC: 2011 Mar 1.

Published in final edited form as: J Hum Genet. 2010 Jun 24;55(9):613–620. doi: 10.1038/jhg.2010.77

Table 1.

Comparison of progression to AIDS outcomes among haplogroup J and hg-I subhaplogroup seroconverters

	CD4 < 200				AIDS-1993				AIDS-1987
(Sub)haplogroup^a	n/events	RH^a	(95% CI)	P	n/events	RH^a	(95% CI)	P	n/events	RH^a	(95% CI)	P
J	97/48	1.00	-		97/49	1.00		-	98/47	1.00		-
I1^*	55/30	1.95	(1.00–3.81)	0.05	55/30	1.83	(0.96–3.48)	0.07	55/29	1.62	(0.84–3.13)	0.15
I2a^*	12/6	1.97	(0.71–5.48)	0.19	12/6	1.74	(0.64–4.78)	0.28	12/5	1.97	(0.65–5.96)	0.22
I2b^*	23/11	2.85	(1.21–6.70)	0.02	23/11	2.56	(1.11–5.93)	0.03	24/10	2.13	(0.93–4.89)	0.07
I^*	4/1	1.70	(0.22–13.16)	0.61	4/2	3.21	(0.71–14.50)	0.36	4/3	4.96	(1.30–18.91)	0.02
I (all)	97/48	2.07	(1.12–3.81)	0.02	97/49	2.02	(1.12–3.64)	0.02	98/47	2.02	(1.11–3.68)	0.02
Within hg-I subhaplogroups
I1^*	55/30	0.74	(0.37–1.48)	0.40	55/30	0.77	(0.39–1.49)	0.43	55/29	0.71	(0.36–1.39)	0.32
I2a^*	12/6	0.98	(0.38–2.54)	0.97	12/6	0.88	(0.34–2.27)	0.79	12/5	1.06	(0.37–3.02)	0.91
I2b^*	23/11	1.60	(0.74–3.46)	0.23	23/11	1.44	(0.67–3.10)	0.35	24/10	1.28	(0.60–2.73)	0.53
I^*	4/1	0.85	(0.09–8.27)	0.89	4/2	2.30	(0.39–13.62)	0.36	4/3	3.69	(0.52–26.21)	0.19

Haplogroup J is the reference group. For within hg-I subhaplogroup comparisons, the reference group is all other subhaplogroups combined against the subhaplogroup of interest. Due to small sample size (n=3) there were no events in the I2a2

group and similar analyses were not conducted.