Table 1.
Agent | Earliest trimester of exposure | |
---|---|---|
1st trimester birth defects/live births | 2nd/3rd trimester birth defects/live births | |
Lamivudine | 99/3481 (2.8%) | 130/5194 (2.5%) |
Adefovir | 0/37 | 0/0 |
Telbivudine | 0/5 | 0/3 |
Tenofovir | 19/879 (2.2%) | 11/501 (2.2%) |
Entecavir | 0/12 | 0/2 |
Any HBV nucleoside/nucleotide | 118/4414 (2.7%) | 141/5700 (2.5%) |
HBV—hepatitis B virus