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. 2010 Aug 26;9(4):231–238. doi: 10.1007/s11901-010-0055-1

Table 2.

General recommendations for the use of PEG-IFN as first-line therapy for HBeAg-positive chronic hepatitis B

HBV genotype General recommendation
A Either high (≥2 × ULN) ALT or low (<9 log10 cp/mL) HBV DNA levels
B and C Both high (≥2 × ULN) ALT and low (<9 log10 cp/mL) HBV DNA levels
D PEG-IFN therapy is not recommended

ALT alanine aminotransferase; HBeAg hepatitis B e antigen; HBV hepatitis B virus; PEG-IFN pegylated interferon; ULN upper limit of normal

(Data from Buster et al. [24••])