FIGURE 4.

TH2-3 regulates LPS-induced release of proinflammatory cytokines. RAW264.7 cell culture supernatants of untreated control, TH2-3-, LPS-, pre-, co-, and post-treated conditions for 24 h were analyzed by a cytokine array kit, and the cytokine secretions of TNF-α (A), IL-1α (B), IL-1β (C), IL-6 (D), IL-10 (E), IL-13 (F), VEGF (G), IL-4 (H), and IL-5 (I) are expressed as relative percentages to the IgG positive control. Mixtures of three independent experimental samples were used for the cytokine array, and the result is the mean of two replicate values. Error bars, S.E. *, values differ at p < 0.05.